SUN-337 Anti-tumorigenic Effects Of The Maternal Leucine Zipper Kinase (MELK) Inhibitor, OTSSP167, In Pre-clinical In Vivo Models Of Adrenocortical Carcinomas (ACC)

ACC is an aggressive endocrine cancer with limited therapeutic options and poor survival rates. In patients with progressive disease, standard EDP (etoposide, doxorubicin and cisplatin) chemotherapy is associated with only a modest response and progression free survival of 5 months. Mitotane, the on...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Endocr Soc
Egile Nagusiak: KAR, ADWITIYA, Zhang, Yu, Yacob, Beteleham, Tompkins, Kenneth, Bagby, Stacey, Leong, Stephen, Pitts, Todd, Wierman, Margaret, Kiseljak-Vassiliades, Katja
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2019
Gaiak:
Tumor Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552789/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-337
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