SUN-337 Anti-tumorigenic Effects Of The Maternal Leucine Zipper Kinase (MELK) Inhibitor, OTSSP167, In Pre-clinical In Vivo Models Of Adrenocortical Carcinomas (ACC)

ACC is an aggressive endocrine cancer with limited therapeutic options and poor survival rates. In patients with progressive disease, standard EDP (etoposide, doxorubicin and cisplatin) chemotherapy is associated with only a modest response and progression free survival of 5 months. Mitotane, the on...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: KAR, ADWITIYA, Zhang, Yu, Yacob, Beteleham, Tompkins, Kenneth, Bagby, Stacey, Leong, Stephen, Pitts, Todd, Wierman, Margaret, Kiseljak-Vassiliades, Katja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2019
Schlagworte:
Tumor Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552789/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-337
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