Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D

BACKGROUND: Pericytes of the blood–brain barrier (BBB) are embedded within basement membrane between brain microvascular endothelial cells (BMECs) and astrocyte end-feet. Despite the direct cell–cell contact observed in vivo, most in vitro BBB models introduce an artificial membrane that separates p...

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Vydáno v:Fluids Barriers CNS
Hlavní autoři: Jamieson, John J., Linville, Raleigh M., Ding, Yuan Yuan, Gerecht, Sharon, Searson, Peter C.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551886/
https://ncbi.nlm.nih.gov/pubmed/31167667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0136-7
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