Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D

BACKGROUND: Pericytes of the blood–brain barrier (BBB) are embedded within basement membrane between brain microvascular endothelial cells (BMECs) and astrocyte end-feet. Despite the direct cell–cell contact observed in vivo, most in vitro BBB models introduce an artificial membrane that separates p...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Jamieson, John J., Linville, Raleigh M., Ding, Yuan Yuan, Gerecht, Sharon, Searson, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551886/
https://ncbi.nlm.nih.gov/pubmed/31167667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0136-7
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