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Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior

Microvessels of the blood-brain barrier (BBB) regulate transport into the brain. The highly specialized brain microvascular endothelial cells, a major component of the BBB, express tight junctions and efflux transporters which regulate paracellular and transcellular permeability. However, most exist...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Linville, Raleigh M., DeStefano, Jackson G., Sklar, Matt B., Xu, Zinnia, Farrell, Alanna M., Bogorad, Max I., Chu, Chengyan, Walczak, Piotr, Cheng, Linzhao, Mahairaki, Vasiliki, Whartenby, Katharine A., Calabresi, Peter A., Searson, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289621/
https://ncbi.nlm.nih.gov/pubmed/30391800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.10.023
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