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Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior

Microvessels of the blood-brain barrier (BBB) regulate transport into the brain. The highly specialized brain microvascular endothelial cells, a major component of the BBB, express tight junctions and efflux transporters which regulate paracellular and transcellular permeability. However, most exist...

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Vydáno v:Biomaterials
Hlavní autoři: Linville, Raleigh M., DeStefano, Jackson G., Sklar, Matt B., Xu, Zinnia, Farrell, Alanna M., Bogorad, Max I., Chu, Chengyan, Walczak, Piotr, Cheng, Linzhao, Mahairaki, Vasiliki, Whartenby, Katharine A., Calabresi, Peter A., Searson, Peter C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289621/
https://ncbi.nlm.nih.gov/pubmed/30391800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.10.023
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