Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation

BACKGROUND: Transwell-based models of the blood–brain barrier (BBB) incorporating monolayers of human brain microvascular endothelial cells (dhBMECs) derived from induced pluripotent stem cells show many of the key features of the BBB, including expression of transporters and efflux pumps, expressio...

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Dades bibliogràfiques
Publicat a:Fluids Barriers CNS
Autors principals: Katt, Moriah E., Linville, Raleigh M., Mayo, Lakyn N., Xu, Zinnia S., Searson, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819713/
https://ncbi.nlm.nih.gov/pubmed/29463314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-018-0092-7
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