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Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation

BACKGROUND: Transwell-based models of the blood–brain barrier (BBB) incorporating monolayers of human brain microvascular endothelial cells (dhBMECs) derived from induced pluripotent stem cells show many of the key features of the BBB, including expression of transporters and efflux pumps, expressio...

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Detaylı Bibliyografya
Yayımlandı:Fluids Barriers CNS
Asıl Yazarlar: Katt, Moriah E., Linville, Raleigh M., Mayo, Lakyn N., Xu, Zinnia S., Searson, Peter C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819713/
https://ncbi.nlm.nih.gov/pubmed/29463314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-018-0092-7
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