Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation

BACKGROUND: Transwell-based models of the blood–brain barrier (BBB) incorporating monolayers of human brain microvascular endothelial cells (dhBMECs) derived from induced pluripotent stem cells show many of the key features of the BBB, including expression of transporters and efflux pumps, expressio...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Katt, Moriah E., Linville, Raleigh M., Mayo, Lakyn N., Xu, Zinnia S., Searson, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819713/
https://ncbi.nlm.nih.gov/pubmed/29463314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-018-0092-7
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