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Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs)

BACKGROUND: The endothelial cells that form the lumen of capillaries and microvessels are an important component of the blood–brain barrier. Cell phenotype is regulated by transducing a range of biomechanical and biochemical signals in the local microenvironment. Here we report on the role of shear...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: DeStefano, Jackson G., Xu, Zinnia S., Williams, Ashley J., Yimam, Nahom, Searson, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543552/
https://ncbi.nlm.nih.gov/pubmed/28774343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-017-0068-z
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