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Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs)

BACKGROUND: The endothelial cells that form the lumen of capillaries and microvessels are an important component of the blood–brain barrier. Cell phenotype is regulated by transducing a range of biomechanical and biochemical signals in the local microenvironment. Here we report on the role of shear...

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Bibliographic Details
Published in:Fluids Barriers CNS
Main Authors: DeStefano, Jackson G., Xu, Zinnia S., Williams, Ashley J., Yimam, Nahom, Searson, Peter C.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543552/
https://ncbi.nlm.nih.gov/pubmed/28774343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-017-0068-z
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