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The role of mutations associated with familial neurodegenerative disorders on blood–brain barrier function in an iPSC model
BACKGROUND: Blood–brain barrier dysfunction is associated with many late-stage neurodegenerative diseases. An emerging question is whether the mutations associated with neurodegenerative diseases can independently lead to blood–brain barrier (BBB) dysfunction. Studies from patient-derived induced pl...
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| Publicado en: | Fluids Barriers CNS |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628493/ https://ncbi.nlm.nih.gov/pubmed/31303172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-019-0139-4 |
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