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Assay for high-throughput screening of inhibitors of the ASC-PYD inflammasome core filament
The protein ASC is a central component of most inflammasome complexes, forming functional oligomeric filaments that activate large amounts of pro-caspase-1 for further IL-1β processing and the induction of Gasdermin D-dependent cell death. The central role of inflammasomes in the innate immune respo...
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| Vydáno v: | Cell Stress |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Shared Science Publishers OG
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6551747/ https://ncbi.nlm.nih.gov/pubmed/31225471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.04.131 |
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