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The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments
Inflammasomes mediate inflammatory and cell death responses to pathogens and cellular stress signals via activation of procaspases-1 and -8. During inflammasome assembly, activated receptors of the NLR or PYHIN family recruit the adaptor protein ASC and initiate polymerization of its pyrin domain (P...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705927/ https://ncbi.nlm.nih.gov/pubmed/26468282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.687731 |
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