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Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection
Cell death is an effective strategy to limit intracellular infections. Canonical inflammasomes, including NLRP3, NLRC4, and AIM2, recruit and activate caspase-1 in response to a range of microbial stimuli and endogenous danger signals. Caspase-1 then promotes the secretion of IL-1β and IL-18 and a r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742712/ https://ncbi.nlm.nih.gov/pubmed/23707339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2013.04.004 |
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