Pyroptotic neuronal cell death mediated by the AIM2 inflammasome

The central nervous system (CNS) is an active participant in the innate immune response to infection and injury. In these studies, we show embryonic cortical neurons express a functional, deoxyribonucleic acid (DNA)-responsive, absent in melanoma 2 (AIM2) inflammasome that activates caspase-1. Neuro...

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Detalhes bibliográficos
Main Authors: Adamczak, Stephanie E, de Rivero Vaccari, Juan Pablo, Dale, Gordon, Brand, Frank J, Nonner, Doris, Bullock, MRoss, Dahl, Gerhard P, Dietrich, W Dalton, Keane, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982080/
https://ncbi.nlm.nih.gov/pubmed/24398937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.236
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