Pyroptotic neuronal cell death mediated by the AIM2 inflammasome

The central nervous system (CNS) is an active participant in the innate immune response to infection and injury. In these studies, we show embryonic cortical neurons express a functional, deoxyribonucleic acid (DNA)-responsive, absent in melanoma 2 (AIM2) inflammasome that activates caspase-1. Neuro...

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Autors principals: Adamczak, Stephanie E, de Rivero Vaccari, Juan Pablo, Dale, Gordon, Brand, Frank J, Nonner, Doris, Bullock, MRoss, Dahl, Gerhard P, Dietrich, W Dalton, Keane, Robert W
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982080/
https://ncbi.nlm.nih.gov/pubmed/24398937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.236
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