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Pyroptotic neuronal cell death mediated by the AIM2 inflammasome
The central nervous system (CNS) is an active participant in the innate immune response to infection and injury. In these studies, we show embryonic cortical neurons express a functional, deoxyribonucleic acid (DNA)-responsive, absent in melanoma 2 (AIM2) inflammasome that activates caspase-1. Neuro...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982080/ https://ncbi.nlm.nih.gov/pubmed/24398937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.236 |
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