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Inflammasomes and host defenses against bacterial infections

The inflammasome has emerged as an important molecular protein complex which initiates proteolytic processing of pro-IL-1β and IL-18 into mature inflammatory cytokines. In addition, inflammasomes initiate pyroptotic cell death that may be independent of those cytokines. Inflammasomes are central to...

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Detalhes bibliográficos
Main Authors: Vladimer, Gregory I., Marty-Roix, Robyn, Ghosh, Shubhendu, Weng, Dan, Lien, Egil
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697846/
https://ncbi.nlm.nih.gov/pubmed/23318142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2012.11.008
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