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ASC filament formation serves as a signal amplification mechanism for inflammasomes
A hallmark of inflammasome activation is the ASC speck, a micrometre-sized structure formed by the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD), which consists of a pyrin domain (PYD) and a caspase recruitment domain (CARD). Here we show that assembly...
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| I publikationen: | Nat Commun |
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| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917984/ https://ncbi.nlm.nih.gov/pubmed/27329339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11929 |
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