The inflammasome adapter ASC assembles into filaments with integral participation of its two Death Domains, PYD and CARD

The inflammasome is a multiprotein complex necessary for the onset of inflammation. The adapter protein ASC assembles inflammasome components by acting as a molecular glue between danger-signal sensors and procaspase-1. The assembly is mediated by ASC self-association and protein interactions via it...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Nambayan, Reinard Jeffrey T., Sandin, Suzanne I., Quint, David A., Satyadi, David M., de Alba, Eva
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333874/
https://ncbi.nlm.nih.gov/pubmed/30459235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004407
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars