Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) optimizes the match between ventilation and perfusion in the lung by reducing blood flow to poorly ventilated regions. Sepsis and endotoxemia impair HPV. We previously showed that nitric oxide synthase 2 (NOS2) is required, but not sufficient, for...

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Detaylı Bibliyografya
Yayımlandı:Respir Res
Asıl Yazarlar: Petersen, Bodil, Busch, Cornelius J., Schleifer, Grigorij, Schaack, Dominik, Lasitschka, Felix, Bloch, Kenneth D., Bloch, Donald B., Ichinose, Fumito
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547543/
https://ncbi.nlm.nih.gov/pubmed/31159807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1062-6
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