Cysteinyl Leukotrienes Impair Hypoxic Pulmonary Vasoconstriction in Endotoxemic Mice

BACKGROUND: Sepsis impairs hypoxic pulmonary vasoconstriction (HPV) in patients and animal models contributing to systemic hypoxemia. Levels of cysteinyl leukotrienes are elevated in the bronchoalveolar lavage fluid of patients with sepsis, but the contribution of cysteinyl leukotrienes to the impai...

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Bibliografiske detaljer
Main Authors: Petersen, Bodil, Austen, K. Frank, Bloch, Kenneth D., Hotta, Yukako, Ichinose, Fumito, Kanaoka, Yoshihide, Zapol, Warren M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194098/
https://ncbi.nlm.nih.gov/pubmed/21934409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31822e94bd
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