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Identification of GPR99 Protein as a Potential Third Cysteinyl Leukotriene Receptor with a Preference for Leukotriene E(4) Ligand
The cysteinyl leukotrienes (cys-LTs), leukotriene C(4) (LTC(4)), a conjugation product of glutathione and eicosatetraenoic acid, and its metabolites, LTD(4) and LTE(4), are lipid mediators of smooth muscle constriction and inflammation in asthma. LTD(4) is the most potent ligand for the type 1 cys-L...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630866/ https://ncbi.nlm.nih.gov/pubmed/23504326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.453704 |
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