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Functional recognition of a distinct receptor preferential for leukotriene E(4) in mice lacking the cysteinyl leukotriene 1 and 2 receptors

The cysteinyl leukotrienes (cys-LTs) are a family of potent lipid mediators of inflammation derived from arachidonic acid. Activation of certain cell types results in the biosynthesis and export of leukotriene (LT) C(4), which then undergoes extracellular metabolism to LTD(4) and LTE(4). LTE(4), the...

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Detalhes bibliográficos
Main Authors: Maekawa, Akiko, Kanaoka, Yoshihide, Xing, Wei, Austen, K. Frank
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575482/
https://ncbi.nlm.nih.gov/pubmed/18931305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808993105
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