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Functional recognition of a distinct receptor preferential for leukotriene E(4) in mice lacking the cysteinyl leukotriene 1 and 2 receptors

The cysteinyl leukotrienes (cys-LTs) are a family of potent lipid mediators of inflammation derived from arachidonic acid. Activation of certain cell types results in the biosynthesis and export of leukotriene (LT) C(4), which then undergoes extracellular metabolism to LTD(4) and LTE(4). LTE(4), the...

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Autori principali: Maekawa, Akiko, Kanaoka, Yoshihide, Xing, Wei, Austen, K. Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575482/
https://ncbi.nlm.nih.gov/pubmed/18931305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808993105
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