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Functional recognition of a distinct receptor preferential for leukotriene E(4) in mice lacking the cysteinyl leukotriene 1 and 2 receptors
The cysteinyl leukotrienes (cys-LTs) are a family of potent lipid mediators of inflammation derived from arachidonic acid. Activation of certain cell types results in the biosynthesis and export of leukotriene (LT) C(4), which then undergoes extracellular metabolism to LTD(4) and LTE(4). LTE(4), the...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575482/ https://ncbi.nlm.nih.gov/pubmed/18931305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808993105 |
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