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Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis
The cysteinyl leukotrienes (cys-LTs), leukotriene (LT) C(4), LTD(4), and LTE(4), are smooth muscle constrictors that signal via the CysLT(1) receptor. Here we report that the cys-LTs play an important role in chronic pulmonary inflammation with fibrosis induced by bleomycin in mice. Targeted disrupt...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365742/ https://ncbi.nlm.nih.gov/pubmed/14970333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400235101 |
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