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Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction

Cytosolic phospholipase A(2) (cPLA(2)) releases arachidonic acid (AA) from phospholipids in cell membranes. To assess the role of cPLA(2) in hypoxic pulmonary vasoconstriction (HPV), we measured the increase in left lung pulmonary vascular resistance (LPVR) before and during hypoxia produced by left...

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Detalhes bibliográficos
Main Authors: Ichinose, Fumito, Ullrich, Roman, Sapirstein, Adam, Jones, Rosemary C., Bonventre, Joseph V., Serhan, Charles N., Bloch, Kenneth D., Zapol, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC150993/
https://ncbi.nlm.nih.gov/pubmed/12045263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14294
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