Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
Abstract Background ATP-regulated potassium channels (KATP) regulate pulmonary vascular tone and are involved in hypoxic pulmonary vasoconstriction (HPV). In patients with inflammation like sepsis or ARDS, HPV is impaired, resulting in a ventilation-perfusion mismatch and hypoxia. Since increase of...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2018-02-01
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| coleção: | Respiratory Research |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12931-018-0735-x |
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