Cytosolic phospholipase A(2) in hypoxic pulmonary vasoconstriction

Cytosolic phospholipase A(2) (cPLA(2)) releases arachidonic acid (AA) from phospholipids in cell membranes. To assess the role of cPLA(2) in hypoxic pulmonary vasoconstriction (HPV), we measured the increase in left lung pulmonary vascular resistance (LPVR) before and during hypoxia produced by left...

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Hauptverfasser: Ichinose, Fumito, Ullrich, Roman, Sapirstein, Adam, Jones, Rosemary C., Bonventre, Joseph V., Serhan, Charles N., Bloch, Kenneth D., Zapol, Warren M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2002
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC150993/
https://ncbi.nlm.nih.gov/pubmed/12045263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14294
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