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Cysteinyl Leukotrienes Impair Hypoxic Pulmonary Vasoconstriction in Endotoxemic Mice

BACKGROUND: Sepsis impairs hypoxic pulmonary vasoconstriction (HPV) in patients and animal models contributing to systemic hypoxemia. Levels of cysteinyl leukotrienes are elevated in the bronchoalveolar lavage fluid of patients with sepsis, but the contribution of cysteinyl leukotrienes to the impai...

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書誌詳細
主要な著者: Petersen, Bodil, Austen, K. Frank, Bloch, Kenneth D., Hotta, Yukako, Ichinose, Fumito, Kanaoka, Yoshihide, Zapol, Warren M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194098/
https://ncbi.nlm.nih.gov/pubmed/21934409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31822e94bd
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