Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome

Hypoxic pulmonary vasoconstriction (HPV) is a physiological vasomotor response that maintains systemic oxygenation by matching perfusion to ventilation during alveolar hypoxia. Although mitochondria appear to play an essential role in HPV, the impact of mitochondrial dysfunction on HPV remains incom...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Schleifer, Grigorij, Marutani, Eizo, Ferrari, Michele, Sharma, Rohit, Skinner, Owen, Goldberger, Olga, Grange, Robert Matthew Henry, Peneyra, Kathryn, Malhotra, Rajeev, Wepler, Martin, Ichinose, Fumito, Bloch, Donald B., Mootha, Vamsi K., Zapol, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397345/
https://ncbi.nlm.nih.gov/pubmed/30520688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00419.2018
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