Soluble epoxide hydrolase deficiency or inhibition enhances murine hypoxic pulmonary vasoconstriction after lipopolysaccharide challenge

Hypoxic pulmonary vasoconstriction (HPV) is the response of the pulmonary vasculature to low levels of alveolar oxygen. HPV improves systemic arterial oxygenation by matching pulmonary perfusion to ventilation during alveolar hypoxia and is impaired in lung diseases such as the acute respiratory dis...

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Опубликовано в: :Am J Physiol Lung Cell Mol Physiol
Главные авторы: Wepler, Martin, Beloiartsev, Arkadi, Buswell, Mary D., Panigrahy, Dipak, Malhotra, Rajeev, Buys, Emmanuel S., Radermacher, Peter, Ichinose, Fumito, Bloch, Donald B., Zapol, Warren M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206400/
https://ncbi.nlm.nih.gov/pubmed/27815261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00394.2016
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