SYK-CARD9 signaling axis promotes gut fungi-mediated inflammasome activation to restrict colitis and colon cancer

Fungi represent a significant proportion of the gut microbiota. Aberrant immune responses to fungi are frequently observed in inflammatory bowel diseases (IBD) and colorectal cancer (CRC), and mutations in the fungal sensing pathways are associated with the pathogenesis of IBD. Fungal recognition re...

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Publicado no:Immunity
Main Authors: Malik, Ankit, Sharma, Deepika, Malireddi, R. K. Subbarao, Guy, Clifford S., Chang, Ti-Cheng, Olsen, Scott R., Neale, Geoffrey, Vogel, Peter, Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541497/
https://ncbi.nlm.nih.gov/pubmed/30231985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.08.024
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