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Inflammasome activation and assembly at a glance

Inflammasomes are multimeric protein complexes that typically comprise a sensor, an adaptor and the zymogen procaspase-1. An inflammasome assembles in response to a diverse range of pathogen-associated or danger-associated molecular patterns (PAMPs or DAMPs). The inflammasome platform leads to activ...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Malik, Ankit, Kanneganti, Thirumala-Devi
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769591/
https://ncbi.nlm.nih.gov/pubmed/29196474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.207365
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