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The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

Over the past decade, numerous advances have been made in the role and regulation of inflammasomes during pathogenic and sterile insults. An inflammasome complex comprises a sensor, an adaptor, and a zymogen procaspase-1. The functional output of inflammasome activation includes secretion of cytokin...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Sharma, Deepika, Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915194/
https://ncbi.nlm.nih.gov/pubmed/27325789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602089
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