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The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

Over the past decade, numerous advances have been made in the role and regulation of inflammasomes during pathogenic and sterile insults. An inflammasome complex comprises a sensor, an adaptor, and a zymogen procaspase-1. The functional output of inflammasome activation includes secretion of cytokin...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Sharma, Deepika, Kanneganti, Thirumala-Devi
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915194/
https://ncbi.nlm.nih.gov/pubmed/27325789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602089
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