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The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

Over the past decade, numerous advances have been made in the role and regulation of inflammasomes during pathogenic and sterile insults. An inflammasome complex comprises a sensor, an adaptor, and a zymogen procaspase-1. The functional output of inflammasome activation includes secretion of cytokin...

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Publicat a:J Cell Biol
Autors principals: Sharma, Deepika, Kanneganti, Thirumala-Devi
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915194/
https://ncbi.nlm.nih.gov/pubmed/27325789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602089
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