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Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection
Interferons (IFNs) were discovered over a half-century ago as antiviral factors. The role of type I IFNs has been studied in the pathogenesis of both acute and chronic microbial infections. Deregulated type I IFN production results in a damaging cascade of cell death, inflammation, and immunological...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824101/ https://ncbi.nlm.nih.gov/pubmed/24273750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2013.00077 |
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