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Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis
BACKGROUND & AIMS: Inflammatory bowel diseases (IBD) increase risk for colorectal cancer. Mutations in the Mediterranean fever gene (MEFV or pyrin) are associated with hereditary autoinflammatory disease and severe IBD. Expression of MEFV, a sensor protein that the initiates assembly of the infl...
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| Publicado no: | Gastroenterology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847456/ https://ncbi.nlm.nih.gov/pubmed/29203393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.11.276 |
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