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Diverging inflammasome signals in tumorigenesis and potential targeting
Inflammasomes are molecular platforms that assemble upon sensing various intracellular stimuli. Inflammasome assembly leads to activation of caspase-1, thereby promoting the secretion of bioactive interleukin-1β and interleukin-18 and inducing an inflammatory cell death called pyroptosis. Effectors...
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| Veröffentlicht in: | Nat Rev Cancer |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6953422/ https://ncbi.nlm.nih.gov/pubmed/30842595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41568-019-0123-y |
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