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IL-33 regulates the IgA-microbiota axis to restrain IL-1α–dependent colitis and tumorigenesis

Inflammatory bowel diseases (IBD) affect over 5 million individuals in the industrialized world, with an increasing incidence rate worldwide. IBD also predisposes affected individuals to development of colorectal cancer, which is a leading cause of cancer-related deaths in adults. Mutations in genes...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Malik, Ankit, Sharma, Deepika, Zhu, Qifan, Karki, Rajendra, Guy, Clifford S., Vogel, Peter, Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127671/
https://ncbi.nlm.nih.gov/pubmed/27775548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88625
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