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Effect of proximal ligand substitutions on the carbene and nitrene transferase activity of myoglobin

Engineered myoglobins were recently shown to be effective catalysts for abiological carbene and nitrene transfer reactions. Here, we investigated the impact of substituting the conserved heme-coordinating histidine residue with both proteinogenic (Cys, Ser, Tyr, Asp) and non-proteinogenic Lewis basi...

詳細記述

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書誌詳細
出版年:Tetrahedron
主要な著者: Moore, Eric J., Fasan, Rudi
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534480/
https://ncbi.nlm.nih.gov/pubmed/31133770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2019.03.009
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