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Effect of proximal ligand substitutions on the carbene and nitrene transferase activity of myoglobin
Engineered myoglobins were recently shown to be effective catalysts for abiological carbene and nitrene transfer reactions. Here, we investigated the impact of substituting the conserved heme-coordinating histidine residue with both proteinogenic (Cys, Ser, Tyr, Asp) and non-proteinogenic Lewis basi...
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| 發表在: | Tetrahedron |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534480/ https://ncbi.nlm.nih.gov/pubmed/31133770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2019.03.009 |
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