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Effect of proximal ligand substitutions on the carbene and nitrene transferase activity of myoglobin

Engineered myoglobins were recently shown to be effective catalysts for abiological carbene and nitrene transfer reactions. Here, we investigated the impact of substituting the conserved heme-coordinating histidine residue with both proteinogenic (Cys, Ser, Tyr, Asp) and non-proteinogenic Lewis basi...

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書目詳細資料
發表在:Tetrahedron
Main Authors: Moore, Eric J., Fasan, Rudi
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534480/
https://ncbi.nlm.nih.gov/pubmed/31133770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2019.03.009
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