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Metal Substitution Modulates the Reactivity and Extends the Reaction Scope of Myoglobin Carbene Transfer Catalysts

Engineered myoglobins have recently emerged as promising scaffolds for catalyzing carbene-mediated transformations. In this work, we investigated the effect of altering the metal center and its first-sphere coordination environment on the carbene transfer reactivity of myoglobin. To this end, we fir...

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Detalhes bibliográficos
Publicado no:Adv Synth Catal
Main Authors: Sreenilayam, Gopeekrishnan, Moore, Eric J., Steck, Viktoria, Fasan, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875932/
https://ncbi.nlm.nih.gov/pubmed/29606929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201700202
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