Epigenetic evolution and lineage histories of chronic lymphocytic leukemia

Genetic and epigenetic intra-tumoral heterogeneity cooperate to shape the evolutionary course of cancer(1). Chronic lymphocytic leukemia (CLL) is a highly informative model for cancer evolution as it undergoes substantial genetic diversification and evolution with therapy(2,3). The CLL epigenome is...

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書誌詳細
出版年:Nature
主要な著者: Gaiti, Federico, Chaligne, Ronan, Gu, Hongcang, Brand, Ryan Matthew, Kothen-Hill, Steven, Schulman, Rafael, Grigorev, Kirill, Risso, Davide, Kim, Kyu-Tae, Pastore, Alessandro, Huang, Kevin Y., Alonso, Alicia, Sheridan, Caroline, Omans, Nathaniel D., Biederstedt, Evan, Clement, Kendell, Wang, Lili, Felsenfeld, Joshua A., Bhavsar, Erica B., Aryee, Martin J., Allan, John N., Furman, Richard, Gnirke, Andreas, Wu, Catherine J., Meissner, Alexander, Landau, Dan A.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533116/
https://ncbi.nlm.nih.gov/pubmed/31092926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1198-z
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