Epigenetic evolution and lineage histories of chronic lymphocytic leukemia

Genetic and epigenetic intra-tumoral heterogeneity cooperate to shape the evolutionary course of cancer(1). Chronic lymphocytic leukemia (CLL) is a highly informative model for cancer evolution as it undergoes substantial genetic diversification and evolution with therapy(2,3). The CLL epigenome is...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Gaiti, Federico, Chaligne, Ronan, Gu, Hongcang, Brand, Ryan Matthew, Kothen-Hill, Steven, Schulman, Rafael, Grigorev, Kirill, Risso, Davide, Kim, Kyu-Tae, Pastore, Alessandro, Huang, Kevin Y., Alonso, Alicia, Sheridan, Caroline, Omans, Nathaniel D., Biederstedt, Evan, Clement, Kendell, Wang, Lili, Felsenfeld, Joshua A., Bhavsar, Erica B., Aryee, Martin J., Allan, John N., Furman, Richard, Gnirke, Andreas, Wu, Catherine J., Meissner, Alexander, Landau, Dan A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533116/
https://ncbi.nlm.nih.gov/pubmed/31092926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1198-z
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