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Estrogen Inhibition Reverses Pulmonary Arterial Hypertension and Associated Metabolic Defects

Increased estrogen is a strong epidemiologic risk factor for development of pulmonary arterial hypertension (PAH) in patients, associated with metabolic defects. Estrogens also drive penetrance in mice carrying mutations in BMPR2, the cause of most heritable PAH. The goal of the present study was to...

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Bibliografiske detaljer
Udgivet i:Eur Respir J
Main Authors: Chen, Xinping, Austin, Eric D., Talati, Megha, Fessel, Joshua P, Farber-Eger, Eric H., Brittain, Evan L., Hemnes, Anna R, Loyd, James E., West, James
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532788/
https://ncbi.nlm.nih.gov/pubmed/28775043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.02337-2016
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