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Estrogen Inhibition Reverses Pulmonary Arterial Hypertension and Associated Metabolic Defects

Increased estrogen is a strong epidemiologic risk factor for development of pulmonary arterial hypertension (PAH) in patients, associated with metabolic defects. Estrogens also drive penetrance in mice carrying mutations in BMPR2, the cause of most heritable PAH. The goal of the present study was to...

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書目詳細資料
發表在:Eur Respir J
Main Authors: Chen, Xinping, Austin, Eric D., Talati, Megha, Fessel, Joshua P, Farber-Eger, Eric H., Brittain, Evan L., Hemnes, Anna R, Loyd, James E., West, James
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532788/
https://ncbi.nlm.nih.gov/pubmed/28775043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.02337-2016
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