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Estrogen Inhibition Reverses Pulmonary Arterial Hypertension and Associated Metabolic Defects

Increased estrogen is a strong epidemiologic risk factor for development of pulmonary arterial hypertension (PAH) in patients, associated with metabolic defects. Estrogens also drive penetrance in mice carrying mutations in BMPR2, the cause of most heritable PAH. The goal of the present study was to...

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Podrobná bibliografie
Vydáno v:Eur Respir J
Hlavní autoři: Chen, Xinping, Austin, Eric D., Talati, Megha, Fessel, Joshua P, Farber-Eger, Eric H., Brittain, Evan L., Hemnes, Anna R, Loyd, James E., West, James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532788/
https://ncbi.nlm.nih.gov/pubmed/28775043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.02337-2016
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