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Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a lethal disorder characterized by pulmonary arterial remodeling, increased right ventricular systolic pressure (RVSP), vasoconstriction and inflammation. The heritable form of PAH (HPAH) is usually (>80%) caused by mutations in the bone morphogenic protei...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Discov Today
Päätekijät: West, James, Austin, Eric, Fessel, Joshua P., Loyd, James, Hamid, Rizwan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396626/
https://ncbi.nlm.nih.gov/pubmed/24794464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.04.015
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