Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes

BACKGROUND: Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by mutations affecting UBE3A gene expression. Previous studies in mice revealed distinct critical periods during neurodevelopment in which reactivation of Ube3a gene expression can prevent the onset of behavioral defic...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Autism
Main Authors: Sonzogni, Monica, Hakonen, Johanna, Bernabé Kleijn, Mireia, Silva-Santos, Sara, Judson, Matthew C., Philpot, Benjamin D., van Woerden, Geeske M., Elgersma, Ype
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532248/
https://ncbi.nlm.nih.gov/pubmed/31143434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-019-0277-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker