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Ube3a loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice
Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss of the maternally inherited allele of UBE3A. Ube3a(STOP/p+) mice recapitulate major features of AS in humans and allow conditional reinstatement of maternal Ube3a with the expression of Cre recombinase. We have recently shown tha...
Uloženo v:
| Vydáno v: | J Neurophysiol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511875/ https://ncbi.nlm.nih.gov/pubmed/28468997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00618.2016 |
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